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Home/Products/Filter Membranes & Syringe Filters/Nylon Disc Membrane Filter

Filter Membranes & Syringe Filters

Nylon Disc Membrane Filter

Product ID: nylon-membrane-disk-filter|Nylon Disc Membrane

Provides high-quality Nylon-6 hydrophilic microporous filter membranes with excellent thermal stability and broad chemical compatibility. It can directly filter aqueous phase, alcohols and various organic solvents without pre-wetting, making it the first choice for HPLC sample and mobile phase pretreatment. It has high protein and nucleic acid (DNA/RNA) binding capacity and is suitable for diagnostic kit manufacturing and gene probe research. Available in No substrate and on PET specifications to ensure optimal flow rate and structural strength.

High-quality Nylon-6 hydrophilic microporous membrane
Excellent thermal stability and broad chemical compatibility
Filters aqueous, alcohol and many organic solvents without pre-wetting
High protein and nucleic acid (DNA/RNA) binding capacity
Available unsupported (no substrate) or PET-supported (on PET)

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Micron rating: 0.1 – 5 µm
Max operating temperature: 80 °C
Nominal outer diameter: Ø13 / Ø25 / Ø47 / Ø50 / Ø90 mm
Removal efficiency: Particle retention, with high binding af

Applications

HPLC sample and mobile phase prep

Aqueous, alcohol and organic solvent filtration

Diagnostic kit manufacturing

Gene probe and nucleic acid research

Specifications

Filter media / membrane: Nylon-6 hydrophilic microporous membrane with good thermal stability and broad chemical compatibility. Naturally hydrophilic, so aqueous, alcohol and many organic solvent samples need no pre-wetting.
Support & drainage layers: Supplied unsupported (no substrate) or PET-supported (on PET). The PET support gives greater structural strength, while the unsupported version favours flow rate.
Micron rating: 0.1 – 5 µm
Removal efficiency: Particle retention, with high binding affinity for proteins and nucleic acids (DNA/RNA) — exactly what diagnostic kit manufacturing and gene probe work require. Where the protein in the sample must be recovered without adsorptive loss, choose a low-binding membrane instead.
Nominal outer diameter: Ø13 / Ø25 / Ø47 / Ø50 / Ø90 mm
Max operating temperature: 80 °C
Wetting & flushing: Hydrophilic. No pre-wetting is required before filtering aqueous, alcohol or most organic solvent samples.
Integrity test: Being hydrophilic, the membrane can be wetted with water directly for bubble point testing.

Note: actual compatibility and service life depend on chemical concentration, temperature, flow, differential pressure, upstream contamination load and housing design. Validate under your real process conditions.

Values shown are typical for this product class; actual supply specification follows the quotation and sample datasheet.

Part Number BuilderJY-LB41

Example part number

-LB41

JY: JIUNYUAN Technology
LB41: Nylon-6 hydrophilic microporous membrane — aqueous, alcohol and most organic solvent samples need no pre-wetting
25: Ø25 mm
P45: 0.45 µm
E: PET-supported
100: 100 discs per box

Selectable options by segment

Disc diameter

Code	Specification
13	Ø13 mm
25	Ø25 mm
47	Ø47 mm
50	Ø50 mm
90	Ø90 mm

A membrane disc has no cartridge-style diameter / rating / length triplet, so the code runs diameter × pore size × support × box quantity. Geometric disc areas per diameter are in the dimensions table on the specification page; the holder sealing ring makes the effective area smaller.

Retention rating

Code	Specification
P10	0.1 µm
P20	0.2 µm
P45	0.45 µm
P80	0.8 µm
M001	1 µm
M003	3 µm
M005	5 µm

Support layer

Code	Specification
N	Unsupported (favours flow rate)
E	PET-supported (favours strength)

Discs per box

Code	Specification
050	50 discs per box
100	100 discs per box

Box quantity is a packaging unit only and does not change the membrane specification; other quantities can be specified at order.

Not every combination is a stock item; uncommon combinations are made to order. Confirm with JIUNYUAN sales before ordering.

Dimensions

Membrane discDrawing shows one representative size; the table below gives the exact diameter and length of each code.

Nominal diameter	Membrane disc area
13 mm	1.3 cm²
25 mm	4.9 cm²
47 mm	17.3 cm²
50 mm	19.6 cm²
90 mm	63.6 cm²

Diameters listed are the industry-standard sizes for membrane discs. The area column is the geometric disc area (πd²/4); effective filtration area is smaller and set by the bore of the holder sealing ring.

Details

Where it fits

Nylon membrane discs are mainly an analytical preparation tool: HPLC samples and mobile phases must have particulates removed before they reach the column, otherwise the column inlet gradually blocks and back pressure climbs. They are also used in diagnostic kit manufacturing and gene probe work, where the membrane binding affinity for nucleic acids is exactly the property required.

Key characteristics

Nylon-6 is naturally hydrophilic, so aqueous, alcohol and most organic solvent samples filter without any pre-wetting — mount the disc in the holder and go. One fewer wetting step is one fewer chance of carrying wetting fluid residue into the sample, which for work that depends on a clean baseline matters more than flow rate.

Two support options are offered: unsupported, and on a PET substrate. The PET support is structurally stronger and suits higher differential pressure or frequent handling, while the unsupported version favours flow rate.

Choosing between options

Choose a disc on wettability first and temperature second:

Membrane	Wettability	Max temp	Typical use
Nylon (this)	Hydrophilic; no pre-wetting	80 °C	HPLC preparation, aqueous and alcohols, diagnostic kits
PTFE	Hydrophobic; aqueous needs pre-wetting	250 °C	Gas and vent sterilisation, aerosol sampling, aggressive solvents

Operation & change-out

Use directly with no pre-wetting. Being hydrophilic it also wets with water for a bubble point test, which makes integrity checking simpler than on a hydrophobic membrane. Temperature ceiling is 80 °C.

Nylon binds proteins and nucleic acids (DNA/RNA) strongly. That is the point in diagnostic kit and gene probe work, but where the protein in the sample is what you are trying to recover, adsorptive loss will bias the result low — choose a low-binding membrane for that case.

FAQ

Does it need pre-wetting before use?

No. Nylon-6 membrane is naturally hydrophilic and filters aqueous, alcohol and many organic solvents directly without pre-wetting, making it convenient to use.

Why is it suited to HPLC sample prep?

Its broad chemical compatibility and excellent thermal stability let it handle aqueous and organic mobile phases, making it a preferred membrane for HPLC sample and mobile phase preparation.

Unsupported vs PET-supported?

It is offered unsupported (no substrate) or PET-supported (on PET); the PET support gives greater structural strength while the unsupported version aids flow rate — choose according to your needs.

PTFE Disc Membrane

ptfe-disc-membrane